PENGARUH EKSTRAK ASHITABA TERHADAP KADAR SERUM GLUTAMIC OXALOACETIC TRANSAMINASE DAN SERUM GLUTAMIC PYRUVIC TRANSAMINASE PADA TIKUS DENGAN LUKA BAKAR

Abstract

Background: Serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) are increased in tissue damage. Ashitaba contains many compounds that can reduce serum SGOT and SGPT levels.

Objective: This study was proposed to prove that giving Ashitaba extract could reduce serum SGOT and SGPT levels in rats exposed to burn injury.

Methods: This study used a posttest only control group design with 20 rats as samples. All research samples were treated with second-degree burns and were divided into 2 different groups, the treatment group (given Ashitaba extract 300 mg /kg BW) and the control group. The blood serum was analyzed for SGOT and SGPT test on the 2^nd, 8^th, and 14^th days. For statistical analysis, the Wilcoxon test used to analyze the levels of serum SGOT and SGPT.

Results: There was no significant difference in serum SGOT and SGPT levels between the control and treatment groups on the 2^nd, 8^th, and 14^th days

Conclusion: Ashitaba extract could not reduce serum SGOT and SGPT levels in rats exposed to burn injury.