Sintesis Dan Uji Aktivitas Antioksidan Senyawa Flavonol 2-(3,4,5-Dimetoksifenil)-3-Hidroksi-4h-Kromen-4-On

  • Muhamad Rokhim Universitas Riau
  • Adel Zamri Universitas Riau
  • Hilwan Yuda Teruna Universitas Riau
: https://doi.org/10.36341/jops.v2i2.847

Abstract

Flavonols derivatives of 2'-hydroxycalone have been synthesized under basic condition (KOH). The structures of all compounds were characterized based on the interpretation of spectroscopic data including HPLC, UV, FTIR, NMR and HRMS. Antioxidant activity was evaluated using the DPPH assay which showed that the flavonol 2'-hydroxycalone derivative was potentially active as antioxidants with IC50 values <1000 µg / mL.

Keywords: 2’-hidroksikalkon, Flavonol, 1,1- diphenyl-2-picryl hydrazyl (DPPH)
Published
2019-07-18
Issue
Vol 2 No 2 (2019): Journal Of Pharmacy and Science
Section
Articles

Copyright (c) 2019 Muhamad Rokhim, Adel Zamri, Hilwan Yuda Teruna

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