PENGGUNAAN OBAT ANTIDIABETES PADA PASIEN RAWAT INAP DI RUMAH SAKIT HARAPAN PEMATANGSIANTAR

PENGGUNAAN OBAT ANTIDIABETES PADA PASIEN RAWAT INAP DI RUMAH SAKIT HARAPAN PEMATANGSIANTAR

  • Shofian Syarifuddin Universitas Efarina
  • Ricard Fredrik Marpaung
  • Pinondang Hotria

Abstract

ABSTRACT

Diabetes mellitus (DM) is a global health problem whose incidence is increasing. As many as 346 million people in the world suffer from diabetes, and it is estimated that it will reach 380 million in 2025. According to WHO in 2000, Indonesia is in the fourth of the country with the highest prevalence of diabetes in the world with a number of sufferers of 8.4 million people. The purpose of this study was to determine the pattern of diabetes mellitus drug use at the Harapan Hospital in Pematangsiantar for the period January-March 2020 and to evaluate the antidiabetic drugs which included the righ indication, right dose, right patient, right drug, and the right way of administration. The research was a survey with a retrospective method, the design used was cross sectional, namely the collection of variable data to get an overview of the use of antidiabetic drugs in inpatients at Harapan Hospital in Pematangsiantar for the period January-March 2020. The results showed that patients suffering from diabetes mellitus in The Harapan Hospital period January-March 2020 were more female than male, with 25 female patients (55.6%) and 20 male patients (44.4%). The highest distribution of antidiabetic single-administered was Glimepiride, namely 11 prescriptions (24.4%) and the highest combination was Glimepiride with Metformin 5 prescription (11.1%). The results of the rationality evaluation showed that the use of antidiabetic drugs has the right indication, the right dose, the right patient, the right drug and the right way of administration

Keywords: Diabetes mellitus, antidiabetic, evaluation of rationality, Harapan Hospital

References

Jean-Marie, E. (2018). Diagnosis and classification of diabetes mellitus. Encyclopedia of Endocrine Diseases, 28(S37), 105–109. https://doi.org/10.1016/B978-0-12-801238-3.65822-1
Wild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004). Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care, 27(5), 1047–1053.


American College of Clinical Pharmacy. 2013. Pharmacotherapy Review Programfor Advanced Clinical Pharmacy Practice.and Impaired Glucose Tolerance in Indonesia.
Andayani, Tri Murti. 2006. Analisis Biaya Terapi Diabetes melitus di Rumah Sakit Dr. Sardjito Yogyakarta. Majalah Farmasi Indonesia 2017 (3) 2006.
Annisa. 2004. Komplikasi Diabetes. Terdapat dalam http:/annisalaboratories.com/komplikasi/diabetes.
Arifin, Ibrahim, Prasetyaningrum, Erna, Murti, Tri. Evaluasi Kerasionalan Pengobatan Diabetes Melitus Tipe 2 Pada Pasien Rawat Inap Di Rumah Sakit Bhakti Wira Tamtama Semarang Tahun 2006. Jurnal Ilmu Farmasi dan Farmasi Klinik Vol . 4 No. 1 Juni 2007. Hal 23-29.
Badan Penelitian dan Pengembangan Kesehatan Departemen Kesehatan, Republik Indonesia. 2008. Riset Kesehatan Dasar (RISKESDAS) Laporan Nasional 2007. Jakarta : Kementerian Kesehatan RI.
Brunner & Suddarth. 2002. Keperawatan Medikal Bedah Edisi 8. Jakarta : EGC. Chandra, Budiman. 2008. Metodologi Penelitian Kesehatan. Jakarta : Penerbit Buku Kedokteran EGC.
Cheng AYY, Zinman B, han CR. 2005. Joslin’s Diabetes Melitus. 4 th. Lipincott Williams & Wilimns. Philadelphia.
Davis, N. Stephen et al. Exploring the Substitution of Exenatide for Insulin in Patients With Type 2 Diabetes Treated With Insulin in Combination With Oral Antidiabetes Agents. Diabetes Care Volume 30 Number 11. November 2007.
Departemen Farmakologi dan Terapeutik Fakultas Kedokteran Universitas Indonesia. 2007. Farmakologi dan Terapi. Jakarta : Gaya Baru.
Direktorat Bina Farmasi Komunitas dan Klinik Direktorat Jenderal Bina Kefarmasian dan Alat Kesehatan Departemen Kesehatan RI 2005.
Handoko, T., dan Suharto B. 1995. Insulin Glukagon dan Antidiabetik Dalam Farmakologi dan Terapi, edisi IV, editor: Sulistia G. Ganiswara, Jakarta, Gaya Baru. Halaman 469, 471-472.
Hardman, Joel G, Lee E. Limbird. Goodman & Gilman Dasar Farmakologi Terapi. Edisi 10 Volume 4. Jakarta : EGC.
Hilary, King, Sicree Richard, Green Anders, Roglic Gojka, Wild Sarah. 2004. Global Prevalence of Diabetes: Estimates for the year 2000 and projections for 2030. Diabetes care vol 27 number 5 : 1047 – 1053
http://binfar.kemkes.go.id/v2/wp-content/uploads/2014/02/PC_DM.pdf diakses pada 14 Agustus 2020.
International Diabetes Federation. 2013. IDF Diabetes Atlas Sixth Edition. Belgia : IDF. Hal 13.
Joseph, T. Dipiro, Robert L. Talbert, Gary C. Yee, Gry R. Matzkee, Barbara G. Wells, L. Michael Polsey (Eds.). 2008. Pharmacotherapy A Pathophysiologic Approach. Edisi ke-7, New York : Mc Graw-Hill Medical Publishing Division.
Keputusan Menteri Kesehatan Republik Indonesia Nomor 1197/MENKES/SK/X/2004 tentang Standar Pelayanan Rumah Sakit.
Keputusan Menteri Kesehatan Republik Indonesia Nomor 440/MENKES/SK/XII/2012.
Keputusan Menteri Kesehatan Republik Indonesia Nomor 312/MENKES/SK/IX/ 2013. Tentang Daftar Esensial Obat Nasional 2013.
King H, Aubert RE, Herman WH. 1998. Global Burden of Diabetes, 1995–2025: Prevalence, Numerical Estimates, and Projections.Diabetes Care vol. 21:1414–1431..
Kurniawan,Indra. 2010. Diabetes Melitus Tipe 2 Pada Usia Lanjut. Majalah Kedokteran Indonesia Vol 60.
Mansjoer, arief, dkk. 2001. Kapita Selekta Kedokteran Edisi ketiga Jilid Pertama.
Mihardja, Laurentia dkk. 2009. Prevalence and Determinants of Diabetes Melitus (A Part of Basic Health Research/Riskesdas). Acta Med Indones- Indones J. Intern Med.
Mycek, M.J., Harvey, R.A., dan Champe C.C. 2001. Farmakologi Ulasan Bergambar. Lippincottt’s Illustrated Reviews: Farmacology. Penerjemah Azwar Agoes. Edisi II. Jakarta. Widya Medika.
Mycek, Mary J. 2001. Farmakologi Ulasan Bergambar. Jakarta : Widya Medika. Naditha Arun, Ramachandran Ambady, Snehalatha Chamukuttan, Shetty Ananth.
Samith. 2012. Trends In Prevalence of Diabetes In Asian CountriesWorld Journal of Diabetes vol 3 issue 6. Baishideng.
Nita Yunita, Yuda Ana, Nugraheni Gesnita. 2012. Pengetahuan Pasien Tentang Diabetes dan Obat Anti Diabetes Oral.Jurnal Farmasi Indonesia Vol. 6 No.1 Januari 2012: 38-47.
PERKENI. 2007. Petunjuk Praktis Terapi Insulin Pada Pasien Diabetes Melitus.
Jakarta : Fakultas Kedokteran Universitas Indonesia.
Perkumpulan Endokrinologi Indonesia (PERKENI). 2011. Konsensus Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 di Indonesia. Jakarta: PERKENI.
Price, Sylvia A. 1995. Edisi 4. Patofisiologi : Konsep Klinis Proses-Proses Penyakit. Jakarta : EGC.
Pusat Data dan Informasi Kementerian Kesehatan RI. 2011. Data dan Informasi.Jakarta : Kementerian Kesehatan RI.
Soegondo S. 2005. Prinsip Pengobatan Diabetes, Obat Hipoglikemik Oral dan Insulin. Balai Penerbit FKUI.
Sudoyo, Aru W, Dr.dr. 2006.Buku Ajar Ilmu Penyakit Dalam, Jilid III, Edisi IV. Jakarta: Pusat Penerbitan Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia.
Suryabrata, S. 2010. Metodologi Penelitian. Jakarta : Rajawali Pers.
Swandari, Swestika. 2013. Penggunaan Obat Rasional (POR) 8 Tepat 1 Waspada Efek Samping. http:bppkmalang.com
Tatro, David S. 2009. Drugs Interaction Facts. Wolters Kluwer Health, Inc. San Carlos, California.
Yusmainita. 2005. Pemberdayaan Instalasi Farmasi Rumah Sakit Pemerintah (Bagian I), Medika, No 12 tahun ke XXVIII,Desember 2002, ISSN. 0216- 0910,799-801
Zahtamal, Chandra, F., Suyanto, dan Restuastuti, T. 2007. Faktor-Faktor Risiko Pasien Diabetes Melitus. Berita Kedokteran Masyarakat, Vol. 23, No. 3. Hal. 142-147.
Published
2021-06-30
Section
Articles
pdf (Bahasa Indonesia)
Abstract views: 89
downloads: 81