Formulasi Sediaan Krim dari Ekstrak Kulit Batang Menteng (Baccaurea racemosa)

Penulis

  • Vonny Kurnia Utama Universitas Abdurrab
  • Kony Putriani Universitas Abdurrab
  • Sabrina Hayati Universitas Abdurrab

Kata Kunci:

Ekstrak, Krim

Abstrak

Kulit batang menteng (Baccaurea racemosa) mengandung antioksidan berupa senyawa fenolik dan flavonoid yang mampu menghentikan reaksi berantai pembentukan radikal bebas. Penelitian ini bertujuan untuk membuat formula sediaan krim dan mengetahui aktivitas antioksidan pada sediaan krim ekstrak kulit batang menteng (Baccaurea racemosa). Penelitian ini menggunakan metode eksperimental dengan cara membuat sediaan krim ekstrak etanol 96% kulit batang menteng dengan konsentrasi 0,5%, 1,5% dan 3%. Hasil pada uji organoleptis berbentuk semi solid berbau khas ekstrak kulit batang menteng berwarna coklat muda, coklat dan coklat tua, uji homogenitas F0, F1, F2 dan F3 bersifat homogen. Uji pH F0 (5), F1 (4,5), F2 (4,7) dan F3 (4,8). Uji daya sebar F0 (6,2 cm), F1 (6,1cm) F2 (5,9 cm) dan F3 (5,6 cm). Uji viskositas F0 (887,73 cPs), F1 (748,06 cPs), F2 (839,43 cPs) dan F3 (817,03 cPs). Uji aktivitas antioksidan memakai spektrofotometer UV-Vis diperoleh panjang gelombang 516,80 nm dengan nilai absorbansi 0,725, pada formula 1 (konsentrasi ekstrak 0,5%) diperoleh nilai IC50 sebesar 51,41, formula 2 (konsentrasi ekstrak 1,5%) diperoleh nilai IC50 sebesar 63,43 dan formula 3 (konsentrasi ekstrak 3%) diperoleh nilai IC50 sebesar 48,91. Kandungan antioksidan pada formula 1 dan 2 memiliki aktivitas antioksidan yang kuat sedangkan formula 3 memiliki aktivitas antioksidan yang sangat kuat.

Unduhan

Data unduhan belum tersedia.

Referensi

Marcdante KJ, Robert MK. Nelson: Essentials of Pediatrics. 8th ed.Philadelphia: Elsevier; 2019.

Trihono PP, Alatas H, Tambunan T, Pardede SO. Tata Laksana Sindrom Nefrotik Idiopatik Pada Anak [Internet]. Vol. 20, Unit Kerja Koordinasi Nefrologi IKatan Dokter anaK IndoNesIa KONSENSUS. 2016. 349–352 p. Available from:https://doi.org/10.1016/j.kint.2 019.09.033%0Ahttp://dx.doi.org/10.1016/S01406736(14)605419%0Ahttp://www.kdigo.org/clinical_practice_guidelines/pdf/KDIGOGNGuideline.pdf%0Ahttp://ejournal.unsrat.ac.id

Jerome C. Lane. Pediatric Nephrotic Syndrome [Internet]. Medscape. 2020.Available from: https://emedicine.medscape.com/arti cle/982920-overview

Tapia C, Bashir K. Nephrotic Syndrome [Internet]. StatsPearls Publishing. 2022.Available from: https://www.ncbi.nlm.nih.gov/books/NBK470444/

Downie ML, Gallibois C, Parekh RS, Noone DG. Nephrotic syndrome in infants and children: Pathophysiology and management. Paediatr Int Child Health [Internet].2017;37(4):24858.Availab lefrom:http://doi.org/10.1080/20469 047.2017.1374003

Bergstein JM. Nelson: Ilmu Kesehatan Anak, Vol. 3. 15th ed. Jakarta: Penerbit Buku Kedokteran EGC; 2000.

Siregar RS. Atlas Berwarna: Saripati Penyakit Kulit. 2nd ed. Jakarta: Penerbit Buku Kedokteran EGC; 2005.

Shukla S. Tinea Corporis [Internet]. Medscape. 2020. Available from: https://emedicine.medscape.com/arti cle/1091473-overview Yee G, Aboud AM Al. Tinea Corporis [Internet]. ncbi. 2020. Available from:https://www.ncbi.nlm.nih.gov/books/NBK544360/

Djuanda S. Ilmu Penyakit Kulit dan Kelamin. Jakarta: Balai Penerbit FKUI;2007.42

K. J. Marcdante, R. M.Kliegman, H. B.Jenson and R. E.Behrman, Nelson Ilmu Kesehatan Anak Esensial. Ikatan Dokter Anak Indonesia. ed ke-6, Saunders Elsevier, 2011.

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Diterbitkan

2025-02-25

Cara Mengutip

Utama, V. K., Putriani, K., & Hayati, S. (2025). Formulasi Sediaan Krim dari Ekstrak Kulit Batang Menteng (Baccaurea racemosa). Jurnal Ilmu Kesehatan Abdurrab, 2(3), 45–54. Diambil dari https://jurnal.univrab.ac.id/index.php/jika/article/view/5131

Terbitan

Vol 2 No 3 (2024): Volume 2 Nomor 3 September 2024

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