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Malassezia furfur merupakan jamur lipofilik dan merupakan bagian dari flora normal kulit. Pada kondisi tertentu, Malassezia furfur dapat menyebabkan Pityriasis versicolor (Tinea versicolor). Pityriasis versicolor umumnya dapat diobati dengan antijamur azol. Namun, belakangan diketahui secara luas bahwa Malassezia furfur telah mengalami resistensi. Oleh karena itu, pendekatan nanopartikel dicari. Penelitian ini bertujuan untuk mensintesis dan mengkarakterisasi nanopartikel perak infus kunyit, serta menguji aktivitas antijamur nanopartikel perak terhadap Malassezia furfur. Metode penelitian ini diawali dengan pembuatan infusa kunyit, sintesis nanopartikel perak menggunakan infusa kunyit dan karakterisasi menggunakan spektrofotometer UV-Vis, serta pengujian aktivitas antijamur nanopartikel perak dengan perbandingan 1:2, 1:4, dan 1:6 pada suhu kamar. waktu pengadukan 3 jam, 6 jam, dan 24 jam dengan menggunakan metode sumur. Hasil penelitian menunjukkan bahwa warna larutan berubah dari kuning menjadi coklat kekuningan. Karakterisasi nanopartikel perak menggunakan spektrofotometer UV-Vis diperoleh nilai serapan tertinggi pada perbandingan 1:6 dengan waktu pengadukan 24 jam dengan panjang gelombang 393nm. Uji aktivitas antijamur menunjukkan zona hambat tertinggi pada perbandingan 1:6 dengan waktu pengadukan 6 jam dengan rata-rata diameter zona hambat 8,17mm dan terendah pada perbandingan 1:6 dengan pengadukan. waktu 24 jam dengan rata-rata diameter zona hambat 2,78mm. Infus kunyit dapat digunakan sebagai bioreduksi dalam sintesis nanopartikel perak.
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