Formulation and Test of Characteristics of Hati Tanah Tuber (Angiopteris evecta) Ethanol Extract Gel Preparation
DOI:
https://doi.org/10.36341/jops.v7i1.4129Keywords:
Gel Formulation, Ethanol Extract of Hati Tanah Tuber, Physical Properties of Gel.Abstract
Gel is a semisolid topical preparation that provides a cool sensation, easy to clean easy to spread, and has good absorption on the skin. Hati Tanah tuber (Angiopteris evecta) contain Flavonoids, Tannins, and Saponins compounds that act as antibacterials. This study aims to determine whether the ethanol extract of Hati Tanah tuber can be formulated into an anti-acne gel preparation and whether the physical properties of the gel preparation meet the physical standards. The method used in this study was experiment by making gel preparations of ethanol extract of Hati Tanah tuber with variations in extract concentrations of 0%, 0,5%, 1%, and 5% and testing the physical properties of organoleptic, homogeneity, adhesion, dispersion, and pH. The results obtained showed that the gel preparation formulation add with ethanol extract of Hati Tanah tuber had a distinctive smell and color from ethanol extract of Hati Tanah tuber. The physical properties of gel preparations of ethanol extracts of Hati Tanah tuber, namely F1, F2, and F3 in the adhesion test meet the requirements, in the homogeneity test only F2 meets the requirements. While in the dispersion test, only F1 meets the requirements, and in the pH test only F2 and F3 have pH values that meet the requirements.
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References
Ansel, H.C, 1998, Pengantar Bentuk Sediaan Farmasi. Edisi 4. Jakarta: Universitas Indonesia Press.
Armando, R, 2009, Memproduksi 15 Minyat Atsiri Berkualitas, Jakarta: Penerbit Penebar Swadaya. Jakarta.
Chairunnisa, R., 2017, Uji Daya Hambat Ekstrak Etanol Umbi Hati Tanah (Angiopteris Sp.) Terhadap Staphylococcus aureus, Karya Tulis Ilmiah, Universitas Muhammadiyah Palangkaraya
Departemen Kesehatan Republik Indonesia, 1995, Materia Medika Indonesia Jilid V, Jakarta.
Ditjen POM, 1985, Formularium Kosmetika Indonesia., Jakarta
Direktorat Jendral Pengawasan Obat dan Makanan (Ditjen POM), 2000, Parameter Standar Umum Ekstrak Tumbuhan Obat, Cetakan Pertama, Jakarta.
Ferian, Eriko, 2019, Formulasi Sediaan Salep Fraksi n-Butanol Umbi Hati Tanah., Karya Tulis Ilmiah, Universitas Muhammadiyah Palangkaraya.
Frizky, Erwin M., 2023, Uji Potensiasi Antibakteri Ekstrak Etanol Umbi Hati Tanah Terhadap Bakteri Staphylococcus epidermidis, Karya Tulis Ilmiah, Universitas Muhammadiyah Palangkaraya. Palangkaraya
Handayani, R., Novariyatiin, S. dan Chairunisa, R, 2015,Uji Farmakognostik Tumbuhan Hati Tanah Asal Kota Palangkaraya, Jurnal Surya Medika, 1(1), Hal: 53-61.
Handayani, R., Qamariah, N., & Bestary, Y, 2022, Formulasi Sediaan Gel Hand Sanitizer dengan Kombinasi Ekstrak Lidah Buaya (Aloe vera L.) dan Ekstrak Daun Mengkudu (Morinda citrifolia L), Jurnal Surya Medika (JSM), 8(3), Hal: 282–289.
Munawaroh R., 2015, Perbandingan Kadar Eugenol Minyak Atsiri Bunga Cengkeh (Syzygium aromaticum L.) Meer. & Perry) dari Maluku, Sumatra, Sulawesi, Dan Jawa dengan Medose GC-MS, Pharmacon. Jurnal Farmasi Indonesia, 11(1), Hal: 25–32.
Nikam, S, 2017, Anti-acne Gel of Isotretinoin: Formulation and Evaluation, Asian of Journal Pharmaceutical and Clinical Research, 10(11), Hal: 257-266.
Sani, R.N., Fithri C.N., Ria D.A., dan Jaya M.M, 2014,Analisis Rendemen dan Skrining Fitokimia Ekstrak Etanol Mikroalga Laut Tetraselmis chuii, Jurnal Pangan dan Agroindustri, 2(2), Hal: 121-126.
Shan, W. dan Imam, A, 2018, Formulasi Gel Ekstrak Kulit Manggis (Garcinia mangostana) dengan Variasi Konsentrasi Basis, Farmaka Suplemen. 16(1), Hal: 108-116.
Wardani, D. K, 2023, Standarisasi Ekstrak Etanol Umbi Hati Tanah, Karya Tulis Ilmiah, Universitas Muhammadiyah Palangkaraya
Yusuf, A.L., Nurawaliah, E., dan Harun, N, 2017, Uji Efektivitas Gel Ekstrak Etanol Daun Kelor (Moringa oleifera L.) sebagai Anti jamur Malassezia furfur. Kartika: Jurnal Ilmiah Farmasi, 5(2), Hal: 62-67.
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