Sintesis Dan Uji Aktivitas Antioksidan Senyawa Flavonol 2-(3,4,5-Dimetoksifenil)-3-Hidroksi-4h-Kromen-4-On

Authors

  • Muhamad Rokhim Universitas Riau
  • Adel Zamri Universitas Riau
  • Hilwan Yuda Teruna Universitas Riau

DOI:

https://doi.org/10.36341/jops.v2i2.847

Keywords:

2’-hidroksikalkon, Flavonol, 1,1- diphenyl-2-picryl hydrazyl (DPPH)

Abstract

Flavonols derivatives of 2'-hydroxycalone have been synthesized under basic condition (KOH). The structures of all compounds were characterized based on the interpretation of spectroscopic data including HPLC, UV, FTIR, NMR and HRMS. Antioxidant activity was evaluated using the DPPH assay which showed that the flavonol 2'-hydroxycalone derivative was potentially active as antioxidants with IC50 values <1000 µg / mL.

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Published

2019-07-18

How to Cite

Rokhim, M., Zamri, A., & Yuda Teruna, H. (2019). Sintesis Dan Uji Aktivitas Antioksidan Senyawa Flavonol 2-(3,4,5-Dimetoksifenil)-3-Hidroksi-4h-Kromen-4-On. JOPS (Journal Of Pharmacy and Science), 2(2), 34–37. https://doi.org/10.36341/jops.v2i2.847