REVIEW: PRODUKSI, KARAKTERISASI DAN APLIKASI SELULOSA BAKTERI DI BIDANG FARMASI
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Abstract
Selulosa bakteri merupakan polimer yang memiliki aplikasi yang luas dan menjanjikan dalam berbagai bidang medis. Tujuan dari penelitian tinjauan pustaka ini adalah untuk melakukan penelusuran pustaka untuk mengetahui apakah substrat dan kondisi fermentasi mempengaruhi kualitas selulosa yang dihasilkan dan penggunaannya di bidang farmasi. Metode pengumpulan data yang digunakan adalah dengan melakukan studi kepustakaan dengan menggunakan kata kunci pencarian: produksi dan aplikasi selulosa bakteri. Artikel ini diulas dalam 10 tahun terakhir yang membahas tentang produksi, karakterisasi, dan aplikasi selulosa bakteri dalam bidang farmasi. Artikel tersebut didapat dari berbagai penelitian yang telah dilakukan melalui mesin pencari seperti Google Scholar, PubMed, dan Science Direct. Berbagai penelitian menunjukkan bahwa substrat, konsentrasi starter, suhu, pH, waktu fermentasi dan proses pemurnian sangat mempengaruhi kualitas selulosa yang dihasilkan. Studi karakterisasi yang dilakukan meliputi SEM, TGA, kadar air dan sifat mekanik. Dalam aplikasi farmasi, selulosa bakteri dapat digunakan untuk membuat pembalut luka, pembawa obat, dan bahan masker wajah, serta stabilisator emulsi dan rekayasa jaringan.
Keywords:
Acetobacter xylinum, Bacterial cellulose, Fermentation, Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA)
References
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Mohammadkazemi, F., Azin, M., Ashori, A., 2015. Production of bacterial cellulose using different carbon sources and culture media. Carbohydr. Polym. 117, 518–523. https://doi.org/10.1016/j.carbpol.2014.10.008
Mondal, I.H., 2015. Cellulose and Cellulose Composites Modification, Characterization And Applications. Nova Science, New York.
Muhajir, M., Suryanto, H., Larasati, A., 2018. Struktur dan Sifat Mekanik Film Bacterial Cellulose dengan Disintegrasi Mekanis. JPSE (Journal Phys. Sci. Eng. 3, 55–62. https://doi.org/10.17977/um024v3i22018p055
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