PERBANDINGAN EFEKTIVITAS INFUSA DAN REBUSAN DAUN LANGSAT (Lansium domesticum L) DALAM MENURUNKAN KADAR GLUKOSA  SECARA IN VITRO

dian nurmansyah; Nafila nafila; Hayatush Shalihah; Amanah amanah

doi:10.36341/klinikal_sains.v10i1.2522

dian nurmansyah Akademi Analis Kesehatan Borneo Lestari
Nafila nafila
Hayatush Shalihah
Amanah amanah

: https://doi.org/10.36341/klinikal_sains.v10i1.2522

Abstract

Langsat leaf (Lansium domesticum L) is one of the medicinal plants that can treat diabetes. Diabetes Mellitus is a disease characterized by an increase in blood sugar. Compounds contained in langsat leaves that function to lower blood glucose levels are flavonoids. Flavonoids are protective against damage to cells that produce insulin and can restore insulin receptor sensitivity on cells and even increase insulin sensitivity. This study aims to determine the difference in decreasing glucose levels in vitro with the addition of infusion and decoction of langsat leaves. Glucose levels were measured in vitro using a UV-Vis Sfektorfotometer using the Nelson Somoghy method. The results of the phytochemical screening test showed positive flavonoid compounds, alkaloids, tannins and saponins. The results of data analysis using the Independent T test obtained p-value 0.032 < 0.050. It can be concluded that there is a significant difference in the measurement of glucose levels in vitro with the treatment of infusion and decoction.

Keywords: glucose level, boiled langsat leaf, langsa leaf infuse water, in vitro

References

Al-Kayis, Kiyan, H., & Susanti, H. (2016). Perbandingan metode Samogyi-Nelson dan Anthrone sulfat pada penetapan kadar gula darah pereduksi dalam ubi cilembu (Ipomea batatas L). Jurnal Farmasi Sains dan Komunitas.
Bimark, A., Deepa, B., Abraham, E., Cherian, B., Blaker, J., & Pothan, L. (2011). Structure morphology and Thermal characteristic of banana nanofibers obtained by steam explosion. Bioresource Technol.
Indriwati, Y., Boddhi, E., & Queljoe. (2018). Skrining fitokimia dan uji aktivitas ekstrak etanol daun langsat (Lansium domesticum Corr) terhadap larva aretmia salina Leach dengan metode BSLT. Jurnal Ilmiah Farmasi.
Lim, T. (2012). Edible Medicinal and Non-Medicinal Plants. New York: Springer.
Puspitasari, D. (2018). Pengaruh metode perebusan terhadap uji fitokimia daun magrove (Excoecaria agallocha). Jurnal Universitas Asahan Kisaran.
Sasmita, F., Susetyarini, E., Husamah, & Pantiwati, Y. (2017). Efek ekstrak daun kembang bulan (Thitonia diversifolia) terhadap kadar glukosa darah tikus wistar (Rattus norvegicus) yang diinduksi Alloxan. Biosfera.
Shalihah, H. (2021). Efektivitas air rebusan daun langsat (Lansium domesticum L) terhadap penurunan kadar glukosa secara invitro. Karya Tulis Ilmiah (Unpublished).
Solikhah, T., & Solikhah, G. (2021). Effect of Muntingia calabura L Leaf Extract on Blood glucose levels and body weight of Alloxan-Induced diabetic mice. Pharmacognosy Journal.
Suprijono, A., Kusumaningrum, D., & Kusmita, L. (2018). Pengaruh pemberian ekstrak etanol dan isolat flavonoid teh olong (Camellia Sinensis (L)) terhadap penurunan kadar glukosa secara in vitro. Prosiding Seminar Nasional Unimus.
Wardatun, S., Yulia, I., & Aprizayansyah, A. (2016). Kandungan flavonoid ekstrak metanol ddan ekstrak etil asetat daun sukun (Astocarpus Altilis)Park) dan aktvitasnya terhadap penurunan kada glukosa secara in vitro. Fitofarmaka.
Wiryowidglo, S. (2013). Kimia dan Farmakologi Bahan Alam. Jakarta: Buku Kedokteran