Evaluation of The Use Antituberculosis Drugs and Analysis of Adherence Pulmonary Tuberculosis Patients at The Sidomulyo Health Center, Pekanbaru
Abstract
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. Based on data from the Global Tuberculosis Report in 2022, Indonesia ranks as the second highest TB case after India. This study aims to evaluate the suitability of OAT use in pulmonary tuberculosis patients at the Sidomulyo pekanbaru Health Center from January-December 2022 based on the 2014 Tuberculosis Prevention guidelines by the Ministry of health of the Republic of Indonesia, as well as the relationship between age, duration of treatment,gender, and chronic comorbidities to patient treatment outcomes,and analysis of the level of adherence of pulmonary TB patients. This study is a non-experimental descriptive research with retrospective data retrieval. The results showed that the type of OAT given is OAT type KDT (fixed dose combination) of 99% with a cure rate of 80%. Suitability of indications, dosage and selection of OAT combination has been in accordance with the standards of the National TB guidelines in 2014. Analysis of the relationship between several factors on the results of treatment of patients obtained from the statistical analysis of chi-square test concluded that the age factor (p=0.00001;p<0.05) has a significant relationship while gender (p=0.064;p>0.05), duration of treatment (p=0.860;p>0.05) and chronic comorbidities (p=0.826;p>0.05) had no significant relationship to the patient's treatment outcomes. The level of patient compliance obtained from the results of filling out questionnaires for pulmonary TB patients at the Sidomulyo Health Center has a high compliance of 49%.
References
Anita, N., & Sari, R. P. (2022). Faktor-Faktor Kesembuhan Penderita Tb Paru Dengan Penyakit Penyerta Diabetes Melitus. Adi Husada Nursing Journal,7(2),51.Https://Doi.Org/10.37036/Ahnj.V7i2.197
Biologi, J., Sains, F., Teknologi, D., Makassar, A., & Mar'iyah, K. (N.D.).Patofisiologi Penyakit Infeksi Tuberkulosis. Http://Journal.Uin-Alauddin.Ac.Id/Index.Php/Psb
Dewi Kristini, T., Hamidah, R., Kesehatan Masyarakat,F.,Muhammadiyah Semarang,U., & Kesehatan Provinsi Jawa Tengah, D. (N.D.). Potensi Penularan Tuberculosis Paru Pada Anggota Keluarga Penderita. In Jurnal Kesehatan Masyarakat Indonesia (Vol. 15, Issue 1).Https://Jurnal.Unimus.Ac.Id/Index.Php/Jkmi,
Fristiohady, A., Ihsan, S., & Haringi, E. (N.D.). Evaluasi Penggunaan Obat Antituberkulosis Pada Pasien Tb Paru Di Rumah Sakit Umum Bahteramas Provinsi Sulawesi Tenggara.1(1).
Ismail,A., Handayany, G. N., & Bakri, M. (N.D.). Evaluasi Penggunaan Obat Antituberkulosis (Oat) Pada Pasien Tuberkulosis Paru Di Puskesmas Jumpandang Baru Makassar.
Kemenkes RI. (2016). Peraturan Menteri Kesehatan Republik Indonesia Nomor 67 Tahun 2016 Tentang Penanggulangan Tuberkulosis. Dinas Kesehatan,163.
Konde, C. P., Asrifuddin, A., & Lang, F. L. F. G. (2020).Hubungan Antara Umur, Status Gizi Dan Kepadatan Hunian Dengan Tuberkulosis Paru Di Puskesmas Tuminting Kota Manado. Jurnal Kesmas,9(1),106-113.
Masrifah, D., & Andarini, Y. D. (2020). Evaluasi Penggunaan Obat Antituberkulosis Pada Pasien Tuberkulosis Rawat Jalan Di Rsud Caruban Periode Januari-Maret 2018. Pharmaceutical Journal Of Islamic Pharmacy,4(1),1-7.Https://Doi.Org/10.21111/Pharmasipha.V4i1.4027
Milantika, J., Akib Yuswar, M., Umilia Purwanti, N., Doktor Haji Hadari Nawawi Kota Pontianak, P., & Korespondensi, P. (2022). Rasionalitas Penggunaan Obat Antituberkulosis Pada Pasien Tuberkulosis Paru Rawat Jalan. Journal Syifa Sciences And Clinical Research (Jsscr), 4.Https://Doi.Org/10.37311/Jsscr.V4i3.15602
Nani Desiyani. (2009). Analisis Faktor-Faktoryangberhubungandengankejadian Kanker Payudara Dirumah Sakitpertamina Cilacap. Jurnal Keperawatan Soedirman, 4(2), 67-73.Http://Www.Jks.Fikes.Unsoed.Ac.Id/Index.Php/Jks/Article/View/224/115
Ningsih, A. S. W., Ramadhan, A. M., & Rahmawati, D. (2022). Kajian Literatur Pengobatan Tuberkulosis Paru Dan Efek Samping Obat Antituberkulosis Di Indonesia. Proceeding Of Mulawarman Pharmaceuticals Conferences,15,231-241.Https://Doi.Org/10.25026/Mpc.V15i1.647
Prananda, M. (N.D.). Evaluasi Penggunaan Obat Anti Tuberkulosis Paru Pada Pasien Dewasa Rawat Jalan Di Unit Pengobatan Penyakit Paru-Paru (Up4)Pontianak.
Qiyaam, N., Furqani, N., Junia Hartanti, D., Program Studi Farmasi, D., Ilmu Kesehatan Universitas Muhammadiyah Mataram, F., Program Studi Farmasi,M., & Ilmu Kesehatan, F. (2020). Evaluasi Penggunaan Obat Antituberkulosis (Oat) Pada Pasien Tuberkulosis Paru Di Puskesmas Kediri Lombok Barat Tahun 2018. Jurnal Ilmu Kefarmasian, 1(1).
Sari, K. E. P., Rizkifani, S., & Iswahyudi. (2021). Evaluasi Penggunaan Obat Anti Tuberkulosis Pada Pasien Baru Tuberkulosis Paru Dewasa Rawat Jalan Di Rs Tk. Ii Kartika Husada Kubu Raya Tahun 2020 Kartini.Jurnal Mahasiswa Farmasi Fakultas Kedokteran Untan,5(1),17.
Sunarmi, S., & Kurniawaty, K. (2022). Hubungan Karakteristik Pasien Tb Paru Dengan Kejadian Tuberkulosis. Jurnal 'Aisyiyah Medika, 7(2), 182-187.Https://Doi.Org/10.36729/Jam.V7i2.865
Tirangga, B., Angin, M. P., & Saputri, G. A. R. (2022). Evaluasi Tingkat Kepatuhan Penggunaan Obat Anti Tuberkulosis (Oat) Terhadap Pasien Tuberkulosis Paru Di Puskesmas Way Jepara Kabupaten Lampung Timur.Jurnal Ilmu Kedokteran Dan Kesehatan, 9(2),837-843.
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