UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAUN MATOA (Pometia pinnata J.R. Forst. & G. Forst)
Kata Kunci:
Daun Matoa, Antibakteri, Gram , Gram –Abstrak
Indonesia memiliki banyak tumbuhan yang harus dilestarikan dan dimanfaatkan dengan baik, sebagian besar dari tumbuhan tersebut dapat dimanfaatkan sebagai obat tradisional, salah satunya adalah Daun Matoa (Pometia pinnata J.R. Forst. & G. Forst). Tanaman ini diketahui memiliki kandungan senyawa metabolit sekunder seperti flavonoid, tanin, terpenoid dan saponin yang memiliki kemampuan untuk menghambat mekanisme kerja bakteri. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri dari ekstrak n-heksan, etil asetat dan etanol Daun Matoa Terhadap Bakteri bakteri gram positif Staphylococcus aureus dan Streptococcus mutans serta bakteri gram negatif Escherichia coli dan Klebsiella pneumonia pada konsentrasi 70, 50, 30 dan 10% menggunakan metode difusi cakram (disc diffusion), Ciprofloxacin sebagai kontrol positif dan DMSO sebagai kontrol negatif. hasil yang terbaik yaitu pada ekstrak etil asetat konsentrasi 70% menunjukkan hasil rata-rata pada bakteri Staphylococcus aureus (10,63 mm), bakteri Streptococcus mutans (13,43 mm), Bakteri Eschericia coli (11,23 mm) dan bakteri Klebsiella pneumenia (13,26 mm). Berdasarkan hasil penelitian ini dapat disimpulkan bahwa ekstrak n-heksan, etil asetat dan etanol Daun Matoa (Pometia pinnata J.R. Forst. & G. Forst) memiliki kemampuan dalam menghambat pertumbuhan Bakteri bakteri gram positif Staphylococcus aureus dan Streptococcus mutans serta bakteri gram negatif Escherichia coli dan Klebsiella pneumonia, tetapi pada ekstrak n-heksan daun matoa tidak mampu dalam menghambat pertumbuhan bakteri Staphylococcus aureus.
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